Design of experiment (DoE) is a risk based approach that applies statistical thinking from the design phase to determine relationships between factors affecting a process and the output of that process to achieve process knowledge. This results in establishment of the design space.
DoE allows multiple input factors to be manipulated at once to analyse their effects on the process. The principles of DoE have been applied in a wide range of pharmaceutical development.
In the article below, we use plunger stopper movement (PSM) testing as an example to explore how DoE can help understand the influence of a range of factors affecting product performance.
Find out more about the importance of Design of Experiment by downloading the article below, and see how Smithers can test to appropriate standards, ensuring the integrity and performance characteristics of your pre-filled syringes
and other medical devices
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