General Manager, Analytical Services
United StatesContact Paul
We can undertake contamination and impurity analyses and identification of:
We employ a wide range of analytical techniques to get results:
Application of the Techniques
Our comprehensive (multidimensional) gas chromatography capabilities can assist with the separation and identification of substances in complex mixtures, which would otherwise be masked using traditional chromatographic techniques:
Conventional GC-MS chromatogram for ‘sample X’
This shows two high concentration analytes (peaks A and B), which could potentially mask other compounds with corresponding retention times (due to having similar boiling points to peaks A or B).
Comprehensive GC-MS (GCXGC-ToF-MS) allows the simultaneous separation of analytes based on their boiling points and relative polarity. This allows detection, identification and quantification of compounds which would potentially be interfered with or hidden by other compounds present; especially if there is a wide range of different concentrations of analyte in the sample.
Figures 2 and 3 provide GCxGC-TOF-MS chromatogram for ‘sample X’ in 3D and overhead views, also showing much lower concentration compounds which co-elute with peaks A and B in the conventional GC-MS analysis. The analytes can be seen eluting from left to right in order of boiling point, and from bottom to top based on relative polarity.
GCxGC-TOF-MS of ‘sample X’ - 3D view
GCxGC-TOF-MS of ‘sample X’ - Overhead view
Find out how Smithers can help your organization. Contact us today.