Product Chemistry
Smithers provides product chemistry services for physical and chemical property testing and characterization using sophisticated analytical instrumentation.
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Chemistry tests offered:
*Smithers has experience of performing these tests across a range of product types including plant protection products, biocidal products, veterinary medicines, pharmaceuticals and industrial chemicals:
OCSPP – Office of Chemical Safety and Pollution Prevention
CIPAC – Collaborative International Pesticides Analytical Council
MT – Miscellaneous Techniques EC Test – Council Regulation (EC) No 440/2008
SANCO – European Commission Directorate General Health and Consumer Protection, now known as SANTE
VICH - Veterinary International Conference on Harmonization
|
Guidelines | |
| Product Chemistry* | ||
|
OCSPP 830.6313 | |
|
CIPAC MT 191 | |
|
FAO Pesticide Specifications 8.11.4 | |
|
OCSPP 830.6303 / 830.6302 | |
| Atomic Absorption Spectroscopy | No Guideline | |
| Auto-Ignition (Liquid) | EC Test A15 | |
| Boiling Point | See OECD Guideline | |
| Density Liquid | See OECD Guideline | |
| Density Solid | OCSPP 830.7300 | |
| Density Bulk/Tap | CIPAC MT 186 | |
| Combined Melting and Boiling Point (Differential Scanning Calorimetry) | See OECD Guideline | |
| Corrosion Testing | OCSPP 830.6320 ASTM G31-72 |
|
| Dilution Stability | OCSPP 830.6320 | |
| Dispersability | CIPAC MT 160 / 174 / 180 | |
| Dissociation Constant | OCSPP 830.7370 | |
| Dissolution of Water Soluble Bag | CIPAC MT 176 | |
| Dust Content | CIPAC MT 171 | |
| Dustability | CIPAC MT 34 | |
| Effectiveness of Cleaning Procedures | No Guideline | |
| Emulsifiability | CIPAC MT 36.3 | |
| Emulsion Stability - Colourimetric Method | CIPAC MT 173 | |
| Explosive Properties (DSC) | EC Test A14 | |
| Explosive Properties (Theoretical) | EC Test A14 | |
| Flammability in Contact with Water | EC Test A12 | |
| Flammability (Solids) | OCSPP 830.6315 | |
| Flash Point | EC Test A9 | |
| Flowability | CIPAC MT 172.1 | |
| Persistent Foam | CIPAC MT 47.1 | |
| Friability and Attrition | CIPAC MT 178 / 178.2 | |
| Granulometry | CIPAC MT 170 | |
| Hydrolysis Tier I - III | See OECD Guideline | |
| IR Spectroscopy | No Guideline | |
| Light Stability (Liquid) | No Guideline | |
| Light Stability (Solid) | No Guideline | |
| Low Temperature Stability | CIPAC MT 39.3 | |
| Mass Spectrometry | No Guideline | |
| Melting / Freezing Point | OECD Guideline | |
| Method Development | No Guideline | |
| Method Validation | SANCO/3030/99 or SANCO/3029/99 | |
| Oxidising Properties (Liquid) | EC Test A21 | |
| Oxidising Properties (Solid) | OCSPP 830.6314 | |
| Oxidising Properties (Theoretical) | EC A17 | |
| Packaging Integrity |
Croplife Technical Monograph No.17 |
|
| Partition Coefficient n-Octanol/Water - HPLC Simulation | See OECD Guideline | |
| Partition Coefficient n-Octanol/Water - Shake Flask | OCSPP 830.7570 | |
| Partition Coefficient n-Octanol/Water – Slow Stir | OCSPP 830.7570 | |
|
CIPAC MT 75.3 | |
| Pigment, Binder and Volatiles Content | No Guideline | |
| Pourability | CIPAC MT 148.1 | |
| Preliminary Analysis (5-Batch) | OCSPP 830.1700 | |
| Pyrophoric Properties (in Contact with Air) | EC Test A13 | |
| Relative Density | See OECD Guideline | |
| Scientific Waiver | No Guideline | |
| Self-Ignition Temperature (Solid) | EC Test A16 | |
| Shelf-Life | OCSPP 830.6317 | |
| Sieve Analysis (Air Jet Sieve) | CIPAC MT 58, 59, 170 | |
| Soils Adsorbtion Coefficient by HPLC | See OECD Guideline | |
| Solubility in Organic Solvents | CIPAC MT 181 | |
| Stability in Organic Solvents and Identity of Relevant Degradation Products | ||
| Stability of Dilute Emulsion | CIPAC MT 36.3 | |
| Stability to Metals | OCSPP 830.6313 | |
| Surface Tension | See OECD Guideline | |
| Suspensibility | CIPAC MT 184 | |
| UV / Vis Spectroscopy | OCSPP 830.7050 | |
| Vapour Pressure | OCSPP 830.7950 | |
| Viscosity | OCSPP 830.7100 | |
| Water Preparation (CIPAC) | CIPAC MT 18 | |
| Water Solubility - Low Sol (Column Elution or Slow Stir) | OCSPP 830.7860 | |
| Water Solubility - High Sol (Shake Flask) | OCSPP 830.7840 | |
| Wet Sieve Analysis | CIPAC MT 185 / 182 | |
| Wettability | CIPAC MT 53.3 | |
| Residue Chemistry | ||
| Analytical Method Development and Validation | OCSPP 860.1340 | |
| Animal Feeding Studies | OCSPP 830.1480 | |
| Dislodgeable Foliar Residue Studies | OCSPP 875.2100 | |
| Fish and Shellfish Residue Studies | OCSPP 860.1400 | |
| Groundwater and Surface Water Studies | ||
| Human Food Safety and Residue Analysis | OCSPP 860.1500/860.1480 | |
| Independent Laboratory Validation of Analytical Methods (ILV) | OCSPP 830.1800 | |
| Magnitude of Residue (MOR) and Residue Decline Studies | OCSPP 860.1500 | |
| Maximum Residue Limits Animal Health Medicines | CVM GFI 208, 243, 257 | |
| Operator / Worker Exposure Studies | OCSPP 875.1000 | |
|
Radiovalidation of Analytical Methods using Aged Samples Originating from14C-metabolism, Field or Feeding Studies (Plant, Animal) |
OCSPP 860.1300 | |
| Storage Stability Studies | OCSPP 860.1380 |
*Smithers has experience of performing these tests across a range of product types including plant protection products, biocidal products, veterinary medicines, pharmaceuticals and industrial chemicals:
OCSPP – Office of Chemical Safety and Pollution Prevention
CIPAC – Collaborative International Pesticides Analytical Council
MT – Miscellaneous Techniques EC Test – Council Regulation (EC) No 440/2008
SANCO – European Commission Directorate General Health and Consumer Protection, now known as SANTE
VICH - Veterinary International Conference on Harmonization
